Grassroots Academy is a leading coaching institute at Delhi India, providing in-depth coaching for examinations in the field of Biotechnology, GATE-Biotechnology, GATE Life Science, M.Sc. Biotech Entrance, DBT-JRF Examination.
Friday, May 15, 2020
Monday, July 13, 2015
ANALYSIS OF TRENDS FOR GATE: SUBJECT MOLECULAR BIOLOGY
DR CHARU S
This post analyzes the trend for Molecular biology-based
questions in the GATE paper.
As per the latest
trend for GATE-BT -2015
Total No of questions:
65
Total Number of marks: 100
General aptitude: 10
questions; 15 marks
Biotech: 55 questions; 85 marks
Negative marking for 1 mark questions: 1/3
Negative marking for 2 mark questions: 2/3
Number of questions in
the GATE-BT paper devoted to MB range from 3-7
|
2015
|
2014
|
2013
|
2012
|
2011
|
2010
|
|
3
|
3
|
5
|
6
|
7
|
5
|
In the 2015 GATE-BT
paper
Number of questions
devoted to MB: 5%
Syllabus for MB
Molecular structure of
genes and chromosomes; DNA replication and control; Transcription and its
control; Translational processes; Regulatory controls in prokaryotes and eukaryotes
Students can heave a sigh of relief. Questions for molecular
biology require only basic concepts.
Topic-wise analysis
of the subject
Molecular structure of genes and
chromosomes; DNA and RNA structure, major and minor grooves, supercoiling; topoisomerases,
calculation of G-C content of a DNA, DNA packaging, histones, euchromatin and
heterochromain, nucleosomes,
DNA replication and control; Concept of
replicons, semi-conservative replication, enzymes involved, DNA polymerases,
helicases, nucleases, okazaki fragments, Basic
DNA repair mechanisms
Transcription and its control; cis-acting
sequences and trans-acting factors, promoters, enhancers, transcription factors,
initiation of transcription, sigma factor, termination in prokaryotes; rho
dependant and independent, attenuation, enzymes and promoters for transcription
of rRNA, mRNA and tRNA, mRNA splicing, polyadenylation, DNA binding motifs in proteins,
techniques to identify protein binding sites on DNA
Translational processes; structure of
tRNA, amino acyl synthetases, mRNA and ribosomes, ribosome binding site on
mRNA, peptideyl transferase activity, concept of reading frame and ORF, basics of
post-translational processing, molecular
chaperons, features of the genetic code
Regulatory controls in prokaryotes and
eukaryotes: operons (lac and tryptophan), gene silencing, RNAi, enzyme involved,
DNA methylation, heterochromatization (very basic), Interpretation of data from
various techniques to determine the level of control of gene expression; transcriptional or translational,
Viral life cycles, calculation of MOI (multiplicity of infection)
Molecular basis of diseases: Disease
and their molecular agents.
Each
year, a fairly regular question is from the molecular mechanism of the action
of drugs and antibiotics; generally as a group matching question
Tuesday, September 7, 2010
Grassroots
Grassroots Academy was founded with the vision to impart right mix of education and guidance to students who aspire to etch for themselves a challenging and distinguishing career in the field of Biotechnology. At Grassroots we create success stories by tapping the student’s inherent strengths, empowering him with outstanding competitive skills and channelizing ones core strength in right direction.
To tap the caliber of students we have devised teaching methods which are result oriented and provides one with competitive edge in qualifying GATE -BIOTECHNOLOGY Exam.
We envision to catapult Grassroots into India’s leading institution where one gets an advantage to enter into the most demanding disciplines in science. The great learning environment at the institute provides a platform where the students can come together and compete for the best. The faculty and management possess a high degree of integrity, knowledge and are experts in their respective fields.
Wednesday, June 16, 2010
GATE - Biotechnology Coaching
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